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publications

articles

  • Chalkia D, Chang YC, Derbeneva O, Lvova M, Wang P, Mishmar D, Liu X, Singh LN, Chuang LM, Wallace DC. Mitochondrial DNA associations with East Asian metabolic syndrome. Biochim Biophys Acta Bioenerg 2018 1859(9):878-892
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  • Hess K, Oliverio R, Nguyen P, Le D, Ellis J, Kdeiss B, Ord S, Chalkia D, Nikolaidis N. Concurrent action of purifying selection and gene conversion results in extreme conservation of the major stress-inducible Hsp70 genes in mammals. Sci Rep 2018 Mar 23
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  • Wallace DC, Chalkia D, Singh LN. Mitochondrial Etiology of Psychiatric Disorders-Reply. JAMA Psychiatry. 2017 75(5):527-528
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  • Chalkia D, Singh LN, Leipzig J, Lvova M, Derbeneva O, Lakatos A, Hadley D, Hakonarson H, Wallace DC. Association Between Mitochondrial DNA Haplogroup Variation and Autism Spectrum Disorders. JAMA Psychiatry. 2017 74(11):1161-1168
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  • McCallister C, Siracusa MC, Shirazi F, Chalkia D, Nikolaidis N. Functional diversification and specialization of cytosolic 70-kDa heat shock proteins. Sci Rep 2015 5:9363
 
  • Lott MT, Leipzig JN, Derbeneva O, Xie HM, Sarmady M, Chalkia D, Procaccio V, and Wallace DC. MtDNA analysis using MITOMAP and MITOMASTER. Curr Protoc Bioinformatics 2013 1.23.1-1.23.26

 

 

  • Sharpley MS, Marciniak C, Eckel-Mahan K, McManus m, Crimi M, Lin CS, Masubuchi S, Waymire K, Friend N, Koike M, Chalkia D, MacGregor G, Sassone-Corsi P, DC Wallace. Maternal inheritance of two different mouse mtDNAs is genetically unstable and results in behavioral and memory abnormalities. Cell 2012 151(2):333-43 (See also a Preview by Nick Lane)
 
  • Ji F, Sharpley MS, Derbeneva O, Alves LS, Qian P, Wang Y, Chalkia D, Lvova M, Xu J, Yao W, Simon M, Platt J, Xu S, Angelin A, Huang T, Wang PH, Chuang LM, Moore LG, Qian G, DC Wallace. Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans. Proc Natl Acad Sci USA 2012 109(19): 7391-6
 
  • Chalkia D. Human mitochondrial population genetics catches up: Next generation mtDNA sequencing for human demographic inference. Mitochondrial DNA 2011 22(1–2): 1–2
 
  • Chalkia D. Inheritance of mitochondrial DNA heteroplasmy: Does Kimura's solution work? Mitochondrial DNA 2009 20(5-6):139-144

 

  • Hong Y, Chalkia D, Ko KD, Bhardwaj G, Chang GS, van Rossum DB, RL Patterson. Phylogenetic Profiles Reveal Structural and Functional Determinants of Lipid-binding. J Proteomics Bioinform 2009 2: 139-14

 

  • Chalkia D, N Nikolaidis, W Makalowski, J Klein, M Nei. Origins and evolution of the formin multigene family that is involved in formation of actin filaments. Mol Biol Evol 2008 25:2717-33, 

 

  • Nikolaidis N*, Chalkia D*, DN Watkins, RK Barrow, SH Snyder, D van Rossum, RL Patterson. Ancient origin of the new developmental superfamily danger. PLoS ONE 2007 2(2):e204

 

  • Nikolaidis N, I Makalowska, D Chalkia, W Makalowski, J Klein, M Nei. Origin and evolution of the chicken leukocyte receptor complex. Proc Natl Acad Sci USA 2005 102: 4057-62

 

  • Frantzidou F, E Diza, D Halkia, A Antoniadis. A seroprevalence study of poliovirus antibody in the population of northern Greece. Clin Microbiol Infect 2005 11: 68-71 

 

  • Frantzidou F, A Papa, D Chalkia, A Antoniadis. Retrospective study on poliomyelitis cases in northern Greece. J Clinic Lab Anal 2004 18: 296-8

 

  • Poulakakis N, P Lymberakis, A Antoniou, D Chalkia, E Zouros, M Mylonas, E Valakos. Molecular phylogeny and biogeography of the wall-lizard Podarcis erhardii (Squamata: Lacertidae). Mol Phylogenet Evol 2003 28: 38-46

 

theses

  • ​Chalkia D. Origins and evolution of three multi-domain gene families concerned with basic cellular and developmental processes in eukaryotes. Ph.D. Thesis 2008​ Biology Department | Eberly College of Science | The Pennsylvania State University

 

  • Chalkia D. Study on the morphological and genetic variability of the species Podarcis erhardii (Sauria: Lacertidae) in Western Crete. M.Sc. Thesis 2000 Biology Department | Faculty of Sciences | University of Crete

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